Effects of Immunosuppressive Medications on Oral Health

By Denise Kissell, BSDH, EFDA, MPH

Through immune system research and improved diagnostics over the past few decades, the number of individuals diagnosed with autoimmune-related conditions has significantly increased.¹ In addition, knowledge of potential causes and risk factors has expanded beyond known genetic components to encompass environmental factors, hormones, and lifestyle choices.² Autoimmune conditions are heterogeneous, affecting individuals differently, thereby complicating treatment.³ Effective medications for one type of autoimmune condition, or group of individuals can be less effective for others.⁴ Research has greatly expanded the number of immunosuppressive medications to control autoimmune diseases (ADs) and protect organ or tissue transplants, but there are numerous adverse effects.⁴ Immunosuppression increases the risk for oral and systemic complications, therefore a delicate balance weighs between immune system suppression and protection from serious side effects. Due to the immune system’s complexity, patients may be on a combination pharmacotherapy to manage their condition.⁴

* References can be found in the original article via the link below.
Read Article