Role of Chlorhexidine-Thymol Varnish in Caries Prevention
To date, most of the research on 1% chlorhexidine in 1% thymol varnish (CTV) has been conducted on which population?
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The premise for using CTV is that chlorhexidine produces antibacterial effects, including selective effects against mutans streptococcus (MS).
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Most studies of CTV have been of sufficient duration to show long-term effects on caries incidence.
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In a study of 102 frail elderly patients, following CTV application, there was an initial significant reduction in levels of salivary MS; however, at 12 months, there were no differences in salivary MS levels between the two varnish groups.
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Chlorhexidine is the gold standard antibacterial agent against which other agents are compared for the reduction of supragingival plaque and gingivitis.
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It is well known what role oral hygiene status has on influencing efficacy of CTV.
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A recent systematic review found that there is no conclusive evidence that the application of CTV is effective when regular professional oral prophylaxis is performed.
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Role of Chlorhexidine-Thymol Varnish in Caries Prevention
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